BDBM382283 US10273244, Example 158::US10584135, Example 158

SMILES: Cn1c(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2ccccc2C(F)(F)F)nnc1-c1ccncc1

InChI Key: InChIKey=RLIMJSGHBMXEDY-GHTZIAJQSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 382283   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382283 (US10273244, Example 158 | US10584135, Example 158) Show SMILES Cn1c(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2ccccc2C(F)(F)F)nnc1-c1ccncc1 |r| Show InChI InChI=1S/C24H27F3N6S/c1-31-22(17-7-10-28-11-8-17)29-30-23(31)34-14-4-12-32-15-18-9-13-33(21(18)16-32)20-6-3-2-5-19(20)24(25,26)27/h2-3,5-8,10-11,18,21H,4,9,12-16H2,1H3/t18-,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INDIVIOR UK LIMITED US Patent					Assay Description [3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD...				US Patent US10584135 (2020) BindingDB Entry DOI: 10.7270/Q29S1TFG
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM382283 (US10273244, Example 158 | US10584135, Example 158) Show SMILES Cn1c(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2ccccc2C(F)(F)F)nnc1-c1ccncc1 |r| Show InChI InChI=1S/C24H27F3N6S/c1-31-22(17-7-10-28-11-8-17)29-30-23(31)34-14-4-12-32-15-18-9-13-33(21(18)16-32)20-6-3-2-5-19(20)24(25,26)27/h2-3,5-8,10-11,18,21H,4,9,12-16H2,1H3/t18-,21+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM382283 (US10273244, Example 158 | US10584135, Example 158) Show SMILES Cn1c(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2ccccc2C(F)(F)F)nnc1-c1ccncc1 |r| Show InChI InChI=1S/C24H27F3N6S/c1-31-22(17-7-10-28-11-8-17)29-30-23(31)34-14-4-12-32-15-18-9-13-33(21(18)16-32)20-6-3-2-5-19(20)24(25,26)27/h2-3,5-8,10-11,18,21H,4,9,12-16H2,1H3/t18-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	234	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INDIVIOR UK LIMITED US Patent					Assay Description CHO cells stably expressing human dopamine receptor type 2, long variant (hD2L), coupled to Gα16 protein (CHO-Gα16-hD2L) were re-suspended ...				US Patent US10584135 (2020) BindingDB Entry DOI: 10.7270/Q29S1TFG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM382283 (US10273244, Example 158 | US10584135, Example 158) Show SMILES Cn1c(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2ccccc2C(F)(F)F)nnc1-c1ccncc1 |r| Show InChI InChI=1S/C24H27F3N6S/c1-31-22(17-7-10-28-11-8-17)29-30-23(31)34-14-4-12-32-15-18-9-13-33(21(18)16-32)20-6-3-2-5-19(20)24(25,26)27/h2-3,5-8,10-11,18,21H,4,9,12-16H2,1H3/t18-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	234	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description Functional Calcium Assay at hD2 recombinant receptor. CHO cells stably expressing human dopamine receptor type 2, long variant (hD2L), coupled to G&#...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair