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SMILES: Nc1nc(nc2n(Cc3cccc(c3)C(=O)N3CCCC3)c(=O)[nH]c12)-c1nnc[nH]1

InChI Key: InChIKey=WNEAQYNFQOKMFM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384110   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM384110
PNG
(US10280167, Example 55)
Show SMILES Nc1nc(nc2n(Cc3cccc(c3)C(=O)N3CCCC3)c(=O)[nH]c12)-c1nnc[nH]1
Show InChI InChI=1S/C19H19N9O2/c20-14-13-17(25-16(24-14)15-21-10-22-26-15)28(19(30)23-13)9-11-4-3-5-12(8-11)18(29)27-6-1-2-7-27/h3-5,8,10H,1-2,6-7,9H2,(H,23,30)(H2,20,24,25)(H,21,22,26)
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.27E+3n/an/an/an/a



University of Nottingham



Assay Description
Activation of human TLR7 results in robust production of interferon by plasmacytoid dendritic cells present in human blood. The potential of compound...

Br J Pharmacol 144: 317-22 (2005)


BindingDB Entry DOI: 10.7270/Q2Z60RDV
More data for this
Ligand-Target Pair