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SMILES: CO[C@H]1CCN(C1)c1ncc(OC\C(CN)=C\F)cn1

InChI Key: InChIKey=JXYUYCVRGOBMGR-INJWIWPUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 385388   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM385388 ((E)-3-Fluoro-2-[[2-[(3S)-3-methoxypyrrolidin-1-yl]...) Show SMILES CO[C@H]1CCN(C1)c1ncc(OC\C(CN)=C\F)cn1 |r| Show InChI InChI=1S/C13H19FN4O2/c1-19-11-2-3-18(8-11)13-16-6-12(7-17-13)20-9-10(4-14)5-15/h4,6-7,11H,2-3,5,8-9,15H2,1H3/b10-4+/t11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford					Assay Description Amine oxidase activity of recombinant SSAO, MAOa, and MAOb isoforms are measured using the MAO-Glo™ assay kit from Promega (V1402). Test compounds (w...				J Med Chem 51: 7057-60 (2008) BindingDB Entry DOI: 10.7270/Q2C82CM5
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM385388 ((E)-3-Fluoro-2-[[2-[(3S)-3-methoxypyrrolidin-1-yl]...) Show SMILES CO[C@H]1CCN(C1)c1ncc(OC\C(CN)=C\F)cn1 |r| Show InChI InChI=1S/C13H19FN4O2/c1-19-11-2-3-18(8-11)13-16-6-12(7-17-13)20-9-10(4-14)5-15/h4,6-7,11H,2-3,5,8-9,15H2,1H3/b10-4+/t11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
ELI LILLY AND COMPANY US Patent					Assay Description Amine oxidase activity of recombinant SSAO, MAOa, and MAOb isoforms are measured using the MAO-Glo™ assay kit from Promega (V1402). Test compounds (w...				US Patent US10793552 (2020)
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM385388 ((E)-3-Fluoro-2-[[2-[(3S)-3-methoxypyrrolidin-1-yl]...) Show SMILES CO[C@H]1CCN(C1)c1ncc(OC\C(CN)=C\F)cn1 |r| Show InChI InChI=1S/C13H19FN4O2/c1-19-11-2-3-18(8-11)13-16-6-12(7-17-13)20-9-10(4-14)5-15/h4,6-7,11H,2-3,5,8-9,15H2,1H3/b10-4+/t11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Amine oxidase activity of recombinant SSAO, MAOa, and MAOb isoforms are measured using the MAO-Glo™ assay kit from Promega (V1402). Test compounds (w...				US Patent US10464928 (2019) BindingDB Entry DOI: 10.7270/Q2ZK5K1J
					More data for this Ligand-Target Pair