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SMILES: CCOc1ncc(cn1)N1CCc2c(C1)c(ccc2C(F)(F)F)N1CCN([C@@H](C)C1)C(=O)Cn1ccc(C)n1

InChI Key: InChIKey=ICYLUSUKPSFAPK-IBGZPJMESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 389717   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM389717
PNG
(US9951063, 36)
Show SMILES CCOc1ncc(cn1)N1CCc2c(C1)c(ccc2C(F)(F)F)N1CCN([C@@H](C)C1)C(=O)Cn1ccc(C)n1
Show InChI InChI=1S/C27H32F3N7O2/c1-4-39-26-31-13-20(14-32-26)34-9-8-21-22(16-34)24(6-5-23(21)27(28,29)30)35-11-12-37(19(3)15-35)25(38)17-36-10-7-18(2)33-36/h5-7,10,13-14,19H,4,8-9,11-12,15-17H2,1-3H3/t19-/m0/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.27n/an/an/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...

Bioorg Med Chem Lett 17: 3473-9 (2007)


BindingDB Entry DOI: 10.7270/Q20R9RRK
More data for this
Ligand-Target Pair