BDBM392660 US10301286, Example 76

SMILES: C[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1F)C(C)(C)C)[C@@H](Cc1c(F)cc(C)cc1F)C(O)=O

InChI Key: InChIKey=GNDOGBVCQLMCPW-MAUNHCGISA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 392660   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM392660 (US10301286, Example 76) Show SMILES C[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1F)C(C)(C)C)[C@@H](Cc1c(F)cc(C)cc1F)C(O)=O |r| Show InChI InChI=1S/C30H37ClF3N3O3/c1-17-10-24(32)21(25(33)11-17)13-27(29(39)40)35-8-9-37(18(2)14-35)28(38)23-16-36(30(3,4)5)15-22(23)20-7-6-19(31)12-26(20)34/h6-7,10-12,18,22-23,27H,8-9,13-16H2,1-5H3,(H,39,40)/t18-,22-,23+,27-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.960	n/a	n/a	n/a	n/a
GSK					Assay Description Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...				Bioorg Med Chem Lett 19: 1332-6 (2009) BindingDB Entry DOI: 10.7270/Q2833VCJ
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Rattus norvegicus)	BDBM392660 (US10301286, Example 76) Show SMILES C[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1F)C(C)(C)C)[C@@H](Cc1c(F)cc(C)cc1F)C(O)=O |r| Show InChI InChI=1S/C30H37ClF3N3O3/c1-17-10-24(32)21(25(33)11-17)13-27(29(39)40)35-8-9-37(18(2)14-35)28(38)23-16-36(30(3,4)5)15-22(23)20-7-6-19(31)12-26(20)34/h6-7,10-12,18,22-23,27H,8-9,13-16H2,1-5H3,(H,39,40)/t18-,22-,23+,27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.70	n/a	n/a	n/a	n/a
GSK					Assay Description Experiment Method(1) Construction of Rat MC4 Receptor-Expressing VectorA rat MC4 receptor gene (GenBank Accession No.: NM_013099.2) was introduced in...				Bioorg Med Chem Lett 19: 1332-6 (2009) BindingDB Entry DOI: 10.7270/Q2833VCJ
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM392660 (US10301286, Example 76) Show SMILES C[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1F)C(C)(C)C)[C@@H](Cc1c(F)cc(C)cc1F)C(O)=O |r| Show InChI InChI=1S/C30H37ClF3N3O3/c1-17-10-24(32)21(25(33)11-17)13-27(29(39)40)35-8-9-37(18(2)14-35)28(38)23-16-36(30(3,4)5)15-22(23)20-7-6-19(31)12-26(20)34/h6-7,10-12,18,22-23,27H,8-9,13-16H2,1-5H3,(H,39,40)/t18-,22-,23+,27-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a
GSK					Assay Description Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...				Bioorg Med Chem Lett 19: 1332-6 (2009) BindingDB Entry DOI: 10.7270/Q2833VCJ
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM392660 (US10301286, Example 76) Show SMILES C[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1F)C(C)(C)C)[C@@H](Cc1c(F)cc(C)cc1F)C(O)=O |r| Show InChI InChI=1S/C30H37ClF3N3O3/c1-17-10-24(32)21(25(33)11-17)13-27(29(39)40)35-8-9-37(18(2)14-35)28(38)23-16-36(30(3,4)5)15-22(23)20-7-6-19(31)12-26(20)34/h6-7,10-12,18,22-23,27H,8-9,13-16H2,1-5H3,(H,39,40)/t18-,22-,23+,27-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
GSK					Assay Description Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...				Bioorg Med Chem Lett 19: 1332-6 (2009) BindingDB Entry DOI: 10.7270/Q2833VCJ
					More data for this Ligand-Target Pair