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BDBM392671 US10301286, Example 27

SMILES: COC[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)c1ccc(F)cc1)[C@@H](Cc1ccc2CCCc2c1)C(O)=O

InChI Key: InChIKey=VNDWSHDMSLVWLJ-VBMYVDSUSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 392671   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM392671
PNG
(US10301286, Example 27)
Show SMILES COC[C@H]1CN(CCN1C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)c1ccc(F)cc1)[C@@H](Cc1ccc2CCCc2c1)C(O)=O |r|
Show InChI InChI=1S/C35H38F3N3O4/c1-45-21-28-18-39(33(35(43)44)16-22-5-6-23-3-2-4-24(23)15-22)13-14-41(28)34(42)31-20-40(27-10-7-25(36)8-11-27)19-30(31)29-12-9-26(37)17-32(29)38/h5-12,15,17,28,30-31,33H,2-4,13-14,16,18-21H2,1H3,(H,43,44)/t28-,30+,31-,33+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.00E+3n/an/an/an/a



GSK



Assay Description
Experiment Method(1) Construction of Human MC Receptor-Expressing VectorA human MC4 receptor gene (GenBank Accession No.: NM_005912.2), a human MC1 r...

Bioorg Med Chem Lett 19: 1332-6 (2009)


BindingDB Entry DOI: 10.7270/Q2833VCJ
More data for this
Ligand-Target Pair