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SMILES: CN(c1ccc(cc1)N1c2ccc3CCCCc3c2NC(=O)CC1=O)S(=O)(=O)Cc1ccccc1Cl

InChI Key: InChIKey=MCQQWRYWLJLOLR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393616   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2X purinoceptor 4


(Homo sapiens (Human))		BDBM393616
PNG
(US09969700, 196)
Show SMILES CN(c1ccc(cc1)N1c2ccc3CCCCc3c2NC(=O)CC1=O)S(=O)(=O)Cc1ccccc1Cl
Show InChI InChI=1S/C27H26ClN3O4S/c1-30(36(34,35)17-19-7-3-5-9-23(19)28)20-11-13-21(14-12-20)31-24-15-10-18-6-2-4-8-22(18)27(24)29-25(32)16-26(31)33/h3,5,7,9-15H,2,4,6,8,16-17H2,1H3,(H,29,32)
KEGG

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PC cid
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US Patent
n/an/a 970n/an/an/an/an/an/a



Universita del Piemonte Orientale



Assay Description
The P2X4 receptor antagonist activity of the compounds of the present invention was measured as follows. The 1321N1 cells stably expressing human P2X...

J Med Chem 52: 3001-9 (2009)


BindingDB Entry DOI: 10.7270/Q2542QX3
More data for this
Ligand-Target Pair