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SMILES: COCCN1C(=O)COc2cc(Nc3ncc4ncn(CC5CC5)c4n3)ccc12

InChI Key: InChIKey=ASYGOSMPEMLREJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 400236   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gamma-aminobutyric acid receptor subunit alpha-5


(Homo sapiens (Human))		BDBM400236
PNG
(7-((9-(Cyclopropylmethyl)-9H-purin-2-yl)amino)-4-(...)
Show SMILES COCCN1C(=O)COc2cc(Nc3ncc4ncn(CC5CC5)c4n3)ccc12
Show InChI InChI=1S/C20H22N6O3/c1-28-7-6-26-16-5-4-14(8-17(16)29-11-18(26)27)23-20-21-9-15-19(24-20)25(12-22-15)10-13-2-3-13/h4-5,8-9,12-13H,2-3,6-7,10-11H2,1H3,(H,21,23,24)
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US Patent
 38n/an/an/an/an/an/an/an/a



Ono Pharmaceutical Co., Ltd

US Patent


Assay Description
The GABAAα5/β3/γ2 protein used for the Scintillation Proximity Assay was derived from membranes produced from HEK293 GABAA α5/ ...

US Patent US10016439 (2018)


BindingDB Entry DOI: 10.7270/Q2NC63J0
More data for this
Ligand-Target Pair