BDBM403753 US10336721, Example 3::US10968198, Example 3

SMILES: COCCOc1ccc2nc(ccc2c1)-c1cn(nn1)-c1ccc(F)cc1

InChI Key: InChIKey=BRTOJHZPIDFFDL-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 403753   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM403753 (US10336721, Example 3 | US10968198, Example 3) Show SMILES COCCOc1ccc2nc(ccc2c1)-c1cn(nn1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H17FN4O2/c1-26-10-11-27-17-7-9-18-14(12-17)2-8-19(22-18)20-13-25(24-23-20)16-5-3-15(21)4-6-16/h2-9,12-13H,10-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University US Patent					Assay Description Data obtained for the Example compounds, obtained using the methods described in Example B.				US Patent US10968198 (2021)
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM403753 (US10336721, Example 3 | US10968198, Example 3) Show SMILES COCCOc1ccc2nc(ccc2c1)-c1cn(nn1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H17FN4O2/c1-26-10-11-27-17-7-9-18-14(12-17)2-8-19(22-18)20-13-25(24-23-20)16-5-3-15(21)4-6-16/h2-9,12-13H,10-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Inhibition of the tautomerase activity of MIF was measured using 4-hydroxyphenyl pyruvic acid (HPP) as substrate, largely following previously report...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2RR1WNP
					More data for this Ligand-Target Pair