BDBM40650 11-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3,3,7,8-tetramethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one::6-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyrazol-4-yl)-2,3,9,9-tetramethyl-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one::6-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-2,3,9,9-tetramethyl-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one::6-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-2,3,9,9-tetramethyl-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one::6-(3-keto-1,5-dimethyl-2-phenyl-3-pyrazolin-4-yl)-2,3,9,9-tetramethyl-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one::MLS000097259::SMR000075783::cid_2951463

SMILES: Cc1c(C2Nc3cc(C)c(C)cc3N=C3CC(C)(C)CC(=O)C23)c(=O)n(-c2ccccc2)n1C

InChI Key: InChIKey=NTJXBGJWZBARPD-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 40650   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
nuclear receptor subfamily 4, group A, member 1 (Homo sapiens (Human))	BDBM40650 (11-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyr...) Show SMILES Cc1c(C2Nc3cc(C)c(C)cc3N=C3CC(C)(C)CC(=O)C23)c(=O)n(-c2ccccc2)n1C |t:14| Show InChI InChI=1S/C28H32N4O2/c1-16-12-20-21(13-17(16)2)30-26(25-22(29-20)14-28(4,5)15-23(25)33)24-18(3)31(6)32(27(24)34)19-10-8-7-9-11-19/h7-13,25-26,30H,14-15H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	PCBioAssay	n/a	n/a	>1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (San Diego, CA) NIH Molecular Libraries Screening Cen...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q29C6VTK
					More data for this Ligand-Target Pair
corticotropin releasing factor-binding protein (Homo sapiens (Human))	BDBM40650 (11-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyr...) Show SMILES Cc1c(C2Nc3cc(C)c(C)cc3N=C3CC(C)(C)CC(=O)C23)c(=O)n(-c2ccccc2)n1C |t:14| Show InChI InChI=1S/C28H32N4O2/c1-16-12-20-21(13-17(16)2)30-26(25-22(29-20)14-28(4,5)15-23(25)33)24-18(3)31(6)32(27(24)34)19-10-8-7-9-11-19/h7-13,25-26,30H,14-15H2,1-6H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	PCBioAssay	n/a	n/a	n/a	n/a	>5.30E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2VX0F3D
					More data for this Ligand-Target Pair
BZLF2 (Human herpesvirus 4 type 2)	BDBM40650 (11-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyr...) Show SMILES Cc1c(C2Nc3cc(C)c(C)cc3N=C3CC(C)(C)CC(=O)C23)c(=O)n(-c2ccccc2)n1C |t:14| Show InChI InChI=1S/C28H32N4O2/c1-16-12-20-21(13-17(16)2)30-26(25-22(29-20)14-28(4,5)15-23(25)33)24-18(3)31(6)32(27(24)34)19-10-8-7-9-11-19/h7-13,25-26,30H,14-15H2,1-6H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	PCBioAssay	n/a	n/a	3.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2057DCW
					More data for this Ligand-Target Pair