null
SMILES: CN1CCN2C[C@@H]3CCCN3C[C@@H](C2)Oc2ccc(F)c(c2)-c2cnn3ccc1nc23
InChI Key: InChIKey=SWFYTWFKWTZELX-FUHWJXTLSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM410730![]() (US10377772, Compound N31) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Oncodesign S.A. US Patent | Assay Description The inhibition of LRRK2 kinase was assessed using LRRK2 recombinant protein in an in vitro peptide-based kinase assay.ProtocolA radiometric protein k... | US Patent US10377772 (2019) BindingDB Entry DOI: 10.7270/Q2251MJZ | |||||||||||
More data for this Ligand-Target Pair |