BDBM412289 US10399945, Example 28::US10669239, Compound 28::US10927079, Compound 28
SMILES: Cc1ncc(cn1)-c1nc(C2CCOCC2)c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)cc1C
InChI Key: InChIKey=UYMBMBNJTWACNW-SHQCIBLASA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM412289 (US10399945, Example 28 | US10669239, Compound 28 |...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent | Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co... | US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM412289 (US10399945, Example 28 | US10669239, Compound 28 |...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent | Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co... | US Patent US10927079 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor (Homo sapiens (Human)) | BDBM412289 (US10399945, Example 28 | US10669239, Compound 28 |...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent | Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co... | US Patent US10669239 (2020) | |||||||||||
More data for this Ligand-Target Pair |