BDBM413919 US10421756, Compound 103

SMILES: Nc1ccc(cc1NC(=O)N1Cc2ccncc2C1)-c1ccncn1

InChI Key: InChIKey=FASOYXRDVWLWFU-UHFFFAOYSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 413919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM413919 (US10421756, Compound 103) Show SMILES Nc1ccc(cc1NC(=O)N1Cc2ccncc2C1)-c1ccncn1 Show InChI InChI=1S/C18H16N6O/c19-15-2-1-12(16-4-6-21-11-22-16)7-17(15)23-18(25)24-9-13-3-5-20-8-14(13)10-24/h1-8,11H,9-10,19H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413919 (US10421756, Compound 103) Show SMILES Nc1ccc(cc1NC(=O)N1Cc2ccncc2C1)-c1ccncn1 Show InChI InChI=1S/C18H16N6O/c19-15-2-1-12(16-4-6-21-11-22-16)7-17(15)23-18(25)24-9-13-3-5-20-8-14(13)10-24/h1-8,11H,9-10,19H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair