null
SMILES: NCc1cccc(c1)-n1nc(cc1C(=O)Nc1cc(ccc1F)[C@H](CCC1CC1)n1ccccc1=O)C(F)(F)F
InChI Key: InChIKey=OFQQGSYWUFBMPP-DEOSSOPVSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Plasma kallikrein (Homo sapiens (Human)) | BDBM417016![]() ((+)-1-(3-(aminomethyl)phenyl)-N-(5-(3-cyclopropyl-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 25.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals, Inc. US Patent | Assay Description The effect of compounds of the invention on human plasma kallikrein activity was determined using the chromogenic substrates (DiaPharma Group, Inc., ... | US Patent US10329260 (2019) BindingDB Entry DOI: 10.7270/Q2R78HM5 | |||||||||||
More data for this Ligand-Target Pair |