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SMILES: CC1N(CCn2c1nnc2-c1csc(n1)N1CCOCC1)C(=O)c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=MTMDXBPDMNNXJZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430680   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuromedin-K receptor


(Homo sapiens (Human))		BDBM430680
PNG
(US10544150, Compound 46 | [1,1'-biphenyl]-4-yl(8-m...)
Show SMILES CC1N(CCn2c1nnc2-c1csc(n1)N1CCOCC1)C(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C26H26N6O2S/c1-18-23-28-29-24(22-17-35-26(27-22)30-13-15-34-16-14-30)32(23)12-11-31(18)25(33)21-9-7-20(8-10-21)19-5-3-2-4-6-19/h2-10,17-18H,11-16H2,1H3
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US Patent
<500n/an/an/an/an/an/an/an/a



Ogeda SA

US Patent


Assay Description
The ability of the compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist SB222200 was assessed by an in vitro r...

US Patent US10544150 (2020)


BindingDB Entry DOI: 10.7270/Q2XW4N7G
More data for this
Ligand-Target Pair