null
SMILES: Cc1noc(n1)[C@@H]1CC1C(=O)NCc1ccc(-c2cccc(OC(F)(F)F)c2)c2CCN(CC(=O)N3COCC3(C)C)Cc12
InChI Key: InChIKey=PVKOYWGJWCGPED-WUBHUQEYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human)) | BDBM435342 ((trans)-N-((2-(2-(4,4-dimethyloxazolidin- 3-yl)-2-...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m... | US Patent US10568876 (2020) BindingDB Entry DOI: 10.7270/Q22B91FB | |||||||||||
More data for this Ligand-Target Pair |