BDBM43849 2-[1-[(4-methyl-1,3-thiazol-2-yl)sulfanyl]ethyl]-5-phenyl-3H-thieno[2,3-d]pyrimidin-4-one::2-[1-[(4-methyl-2-thiazolyl)thio]ethyl]-5-phenyl-3H-thieno[2,3-d]pyrimidin-4-one::2-[1-[(4-methylthiazol-2-yl)thio]ethyl]-5-phenyl-3H-thieno[2,3-d]pyrimidin-4-one::Acid, 59::MLS000760573::SMR000369830::cid_4881247

SMILES: CC(Sc1nc(C)cs1)c1nc2scc(-c3ccccc3)c2c(=O)[nH]1

InChI Key: InChIKey=XQAMSKBUGFVQFY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 43849   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA repair protein RAD51 homolog 1 (Homo sapiens (Human))	BDBM43849 (2-[1-[(4-methyl-1,3-thiazol-2-yl)sulfanyl]ethyl]-5...) Show SMILES CC(Sc1nc(C)cs1)c1nc2scc(-c3ccccc3)c2c(=O)[nH]1 Show InChI InChI=1S/C18H15N3OS3/c1-10-8-24-18(19-10)25-11(2)15-20-16(22)14-13(9-23-17(14)21-15)12-6-4-3-5-7-12/h3-9,11H,1-2H3,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2QN6558
					More data for this Ligand-Target Pair
HIV-1 protease (Human immunodeficiency virus)	BDBM43849 (2-[1-[(4-methyl-1,3-thiazol-2-yl)sulfanyl]ethyl]-5...) Show SMILES CC(Sc1nc(C)cs1)c1nc2scc(-c3ccccc3)c2c(=O)[nH]1 Show InChI InChI=1S/C18H15N3OS3/c1-10-8-24-18(19-10)25-11(2)15-20-16(22)14-13(9-23-17(14)21-15)12-6-4-3-5-7-12/h3-9,11H,1-2H3,(H,20,21,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	5.6	37
The Scripps Research Institute					Assay Description Inhibition of HIV-protease activity for selected acids at P3-P3' positions.				Chem Biol 9: 891-6 (2002) Article DOI: 10.1016/S1074-5521(02)00184-9 BindingDB Entry DOI: 10.7270/Q2GM85QP
					More data for this Ligand-Target Pair