null
SMILES: Oc1ccc2CC[C@@H](Cc2c1)NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2ccccc2F)cc1OCc1cncc(c1)C#N
InChI Key: InChIKey=XDCLLEMJTZSHTP-WLMPYFOXSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Programmed cell death 1 ligand 1 (Homo sapiens (Human)) | US11426364, Compound 3.093 (US10639284, Compound 3.093) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Programmed cell death 1 ligand 1 (Homo sapiens (Human)) | BDBM440924 (US10639284, Compound 3.093) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | US Patent | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
ChemoCentryx, Inc. US Patent | Assay Description Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% BSA... | US Patent US10639284 (2020) | |||||||||||
More data for this Ligand-Target Pair |