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SMILES: FC(F)c1cncc(c1)-c1ccc2cnc(NC(=O)c3cccc(c3)C3CCNCC3)cc2c1

InChI Key: InChIKey=MOUGRXYMMZBZET-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 442840   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM442840 (US10653688, Compound 26) Show SMILES FC(F)c1cncc(c1)-c1ccc2cnc(NC(=O)c3cccc(c3)C3CCNCC3)cc2c1 Show InChI InChI=1S/C27H24F2N4O/c28-26(29)24-12-23(14-31-15-24)19-4-5-21-16-32-25(13-22(21)11-19)33-27(34)20-3-1-2-18(10-20)17-6-8-30-9-7-17/h1-5,10-17,26,30H,6-9H2,(H,32,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				US Patent US10653688 (2020) BindingDB Entry DOI: 10.7270/Q2Z322PW
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM442840 (US10653688, Compound 26) Show SMILES FC(F)c1cncc(c1)-c1ccc2cnc(NC(=O)c3cccc(c3)C3CCNCC3)cc2c1 Show InChI InChI=1S/C27H24F2N4O/c28-26(29)24-12-23(14-31-15-24)19-4-5-21-16-32-25(13-22(21)11-19)33-27(34)20-3-1-2-18(10-20)17-6-8-30-9-7-17/h1-5,10-17,26,30H,6-9H2,(H,32,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The DYRK1A kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...				US Patent US10653688 (2020) BindingDB Entry DOI: 10.7270/Q2Z322PW
					More data for this Ligand-Target Pair