null

SMILES: CNC(=O)c1ccc(cn1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1

InChI Key: InChIKey=XLGFQPFROQWIMH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 443325   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
OTU domain-containing protein 7B (Human)	BDBM443325 (5-(1-Cyano-2'-oxo-1',4'-dihydro-2'H- spiro[pyrroli...) Show SMILES CNC(=O)c1ccc(cn1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C20H19N5O2/c1-22-18(26)17-5-3-14(10-23-17)13-2-4-16-15(8-13)9-20(19(27)24-16)6-7-25(11-20)12-21/h2-5,8,10H,6-7,9,11H2,1H3,(H,22,26)(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US10654853 (2020) BindingDB Entry DOI: 10.7270/Q21V5J02
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443325 (5-(1-Cyano-2'-oxo-1',4'-dihydro-2'H- spiro[pyrroli...) Show SMILES CNC(=O)c1ccc(cn1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C20H19N5O2/c1-22-18(26)17-5-3-14(10-23-17)13-2-4-16-15(8-13)9-20(19(27)24-16)6-7-25(11-20)12-21/h2-5,8,10H,6-7,9,11H2,1H3,(H,22,26)(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443325 (5-(1-Cyano-2'-oxo-1',4'-dihydro-2'H- spiro[pyrroli...) Show SMILES CNC(=O)c1ccc(cn1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C20H19N5O2/c1-22-18(26)17-5-3-14(10-23-17)13-2-4-16-15(8-13)9-20(19(27)24-16)6-7-25(11-20)12-21/h2-5,8,10H,6-7,9,11H2,1H3,(H,22,26)(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair