null

SMILES: FC(F)(F)Oc1ccc(Cl)c(c1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1

InChI Key: InChIKey=XOVJWWGPMBQSLT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 443352   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
OTU domain-containing protein 7B (Human)	BDBM443352 (6'-(2-Chloro-5- (trifluoromethoxy)phenyl)-2'-oxo-1...) Show SMILES FC(F)(F)Oc1ccc(Cl)c(c1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C20H15ClF3N3O2/c21-16-3-2-14(29-20(22,23)24)8-15(16)12-1-4-17-13(7-12)9-19(18(28)26-17)5-6-27(10-19)11-25/h1-4,7-8H,5-6,9-10H2,(H,26,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US10654853 (2020) BindingDB Entry DOI: 10.7270/Q21V5J02
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443352 (6'-(2-Chloro-5- (trifluoromethoxy)phenyl)-2'-oxo-1...) Show SMILES FC(F)(F)Oc1ccc(Cl)c(c1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C20H15ClF3N3O2/c21-16-3-2-14(29-20(22,23)24)8-15(16)12-1-4-17-13(7-12)9-19(18(28)26-17)5-6-27(10-19)11-25/h1-4,7-8H,5-6,9-10H2,(H,26,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443352 (6'-(2-Chloro-5- (trifluoromethoxy)phenyl)-2'-oxo-1...) Show SMILES FC(F)(F)Oc1ccc(Cl)c(c1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1 Show InChI InChI=1S/C20H15ClF3N3O2/c21-16-3-2-14(29-20(22,23)24)8-15(16)12-1-4-17-13(7-12)9-19(18(28)26-17)5-6-27(10-19)11-25/h1-4,7-8H,5-6,9-10H2,(H,26,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair