null

SMILES: O=C(Nc1ccccc1)c1ccc2NC(=O)C3(CCN(C3)C#N)Oc2n1

InChI Key: InChIKey=GSFOZGZZBRWSKD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 443370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
OTU domain-containing protein 7B (Human)	BDBM443370 (1′-Cyano-2-oxo-N-phenyl-1,2-dihydrospiro[pyr...) Show SMILES O=C(Nc1ccccc1)c1ccc2NC(=O)C3(CCN(C3)C#N)Oc2n1 Show InChI InChI=1S/C18H15N5O3/c19-11-23-9-8-18(10-23)17(25)22-14-7-6-13(21-16(14)26-18)15(24)20-12-4-2-1-3-5-12/h1-7H,8-10H2,(H,20,24)(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63QX
					More data for this Ligand-Target Pair
OTU domain-containing protein 7B (Human)	BDBM443370 (1′-Cyano-2-oxo-N-phenyl-1,2-dihydrospiro[pyr...) Show SMILES O=C(Nc1ccccc1)c1ccc2NC(=O)C3(CCN(C3)C#N)Oc2n1 Show InChI InChI=1S/C18H15N5O3/c19-11-23-9-8-18(10-23)17(25)22-14-7-6-13(21-16(14)26-18)15(24)20-12-4-2-1-3-5-12/h1-7H,8-10H2,(H,20,24)(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
MISSION THERAPEUTICS LIMITED US Patent					Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...				US Patent US10654853 (2020) BindingDB Entry DOI: 10.7270/Q21V5J02
					More data for this Ligand-Target Pair