null
SMILES: CC(C)N1CCC(O[C@H]2[C@@H](O)C[C@H](O[C@H]3[C@@H](O)C[C@H](O[C@H]4CC[C@@]5(C)C(CCC6C5C[C@H](O)[C@]5(C)[C@H](CC[C@]65O)C5=CC(=O)OC5)C4)O[C@H]3C)O[C@H]2C)OC(C)C1
InChI Key: InChIKey=ZZSCZRRDHAFLAV-AJOSXQTQSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 (Homo sapiens (Human)) | BDBM444979![]() (US10668094, Compound DiP) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 10.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444979![]() (US10668094, Compound DiP) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 16.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-1 (Homo sapiens (Human)) | BDBM444979![]() (US10668094, Compound DiP) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 28.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-1/beta-1 (Homo sapiens (Human)) | BDBM444979![]() (US10668094, Compound DiP) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 149 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) | |||||||||||
More data for this Ligand-Target Pair |