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SMILES: COCCn1c(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(OC)cn2)nnc1-c1cccc(OC)n1

InChI Key: InChIKey=GDLDBLMNQAKYGB-KBPBESRZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 447701   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apelin receptor


(Homo sapiens (Human))		BDBM447701
PNG
(US10689367, Example 20.0)
Show SMILES COCCn1c(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(OC)cn2)nnc1-c1cccc(OC)n1 |r|
Show InChI InChI=1S/C20H27N7O5S/c1-13(18-21-11-15(31-4)12-22-18)14(2)33(28,29)26-20-25-24-19(27(20)9-10-30-3)16-7-6-8-17(23-16)32-5/h6-8,11-14H,9-10H2,1-5H3,(H,25,26)/t13-,14-/m0/s1
PDB

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US Patent
n/an/an/an/a 110n/an/an/an/a



AMGEN INC.

US Patent


Assay Description
The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...

US Patent US10689367 (2020)


BindingDB Entry DOI: 10.7270/Q2P84FXK
More data for this
Ligand-Target Pair