null
SMILES: Cn1ncc2ccc(cc12)C(=O)N[C@@H](CCN1CCC[C@](F)(CCc2ccc3CCCNc3n2)C1)C(O)=O
InChI Key: InChIKey=JICYWLUEAYEBRM-FIPFOOKPSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM448878 (US10696672, Compound 110 | US11634418, Compound 11...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q22J6GS4 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM448878 (US10696672, Compound 110 | US11634418, Compound 11...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <50 | n/a | n/a | n/a | n/a | n/a | n/a |
Pliant Therapeutics, Inc. US Patent | Assay Description Microplates were coated with recombinant human integrin αvβ6 (2 ug/ml) in PBS (100 ul/well 25° C., overnight). The coating solution was rem... | US Patent US10696672 (2020) BindingDB Entry DOI: 10.7270/Q2TT4V06 | |||||||||||
More data for this Ligand-Target Pair |