null

SMILES: CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(F)nc23)cc1

InChI Key: InChIKey=FDPCPAZFWYCATQ-YBEGLDIGSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 454346   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxidized low-density lipoprotein receptor 1 (Bovine)	BDBM454346 (US10717734, Compound 22 | US10717734, Compound 23) Show SMILES CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(F)nc23)cc1 Show InChI InChI=1S/C21H24F2N4O2S/c1-14-18(12-15-4-6-17(7-5-15)30(28,29)26(2)3)21-19(8-9-20(23)25-21)27(14)13-16(22)10-11-24/h4-10H,11-13,24H2,1-3H3/b16-10-	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...				US Patent US10717734 (2020)
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM454346 (US10717734, Compound 22 | US10717734, Compound 23) Show SMILES CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(F)nc23)cc1 Show InChI InChI=1S/C21H24F2N4O2S/c1-14-18(12-15-4-6-17(7-5-15)30(28,29)26(2)3)21-19(8-9-20(23)25-21)27(14)13-16(22)10-11-24/h4-10H,11-13,24H2,1-3H3/b16-10-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...				US Patent US10717734 (2020)
					More data for this Ligand-Target Pair
Oxidized low-density lipoprotein receptor 1 (Bovine)	BDBM454346 (US10717734, Compound 22 | US10717734, Compound 23) Show SMILES CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(F)nc23)cc1 Show InChI InChI=1S/C21H24F2N4O2S/c1-14-18(12-15-4-6-17(7-5-15)30(28,29)26(2)3)21-19(8-9-20(23)25-21)27(14)13-16(22)10-11-24/h4-10H,11-13,24H2,1-3H3/b16-10-	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...				US Patent US10717734 (2020)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM454346 (US10717734, Compound 22 | US10717734, Compound 23) Show SMILES CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(F)nc23)cc1 Show InChI InChI=1S/C21H24F2N4O2S/c1-14-18(12-15-4-6-17(7-5-15)30(28,29)26(2)3)21-19(8-9-20(23)25-21)27(14)13-16(22)10-11-24/h4-10H,11-13,24H2,1-3H3/b16-10-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description MAO-B: The specificity of the compounds of this invention was tested by determining their ability to inhibit MAO-B activities in vitro. Recombinant h...				US Patent US10717734 (2020)
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM454346 (US10717734, Compound 22 | US10717734, Compound 23) Show SMILES CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(F)nc23)cc1 Show InChI InChI=1S/C21H24F2N4O2S/c1-14-18(12-15-4-6-17(7-5-15)30(28,29)26(2)3)21-19(8-9-20(23)25-21)27(14)13-16(22)10-11-24/h4-10H,11-13,24H2,1-3H3/b16-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description SSAO/VAP-1: Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxida...				US Patent US10717734 (2020)
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM454346 (US10717734, Compound 22 | US10717734, Compound 23) Show SMILES CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(F)nc23)cc1 Show InChI InChI=1S/C21H24F2N4O2S/c1-14-18(12-15-4-6-17(7-5-15)30(28,29)26(2)3)21-19(8-9-20(23)25-21)27(14)13-16(22)10-11-24/h4-10H,11-13,24H2,1-3H3/b16-10-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description MAO-B: The specificity of the compounds of this invention was tested by determining their ability to inhibit MAO-B activities in vitro. Recombinant h...				US Patent US10717734 (2020)
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM454346 (US10717734, Compound 22 | US10717734, Compound 23) Show SMILES CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(F)nc23)cc1 Show InChI InChI=1S/C21H24F2N4O2S/c1-14-18(12-15-4-6-17(7-5-15)30(28,29)26(2)3)21-19(8-9-20(23)25-21)27(14)13-16(22)10-11-24/h4-10H,11-13,24H2,1-3H3/b16-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description SSAO/VAP-1: Human recombinant SSAO/VAP-1 amine oxidase activity was determined using the coupled colorimetric method as described for monoamine oxida...				US Patent US10717734 (2020)
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM454346 (US10717734, Compound 22 | US10717734, Compound 23) Show SMILES CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(F)nc23)cc1 Show InChI InChI=1S/C21H24F2N4O2S/c1-14-18(12-15-4-6-17(7-5-15)30(28,29)26(2)3)21-19(8-9-20(23)25-21)27(14)13-16(22)10-11-24/h4-10H,11-13,24H2,1-3H3/b16-10-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...				US Patent US10717734 (2020)
					More data for this Ligand-Target Pair