null
SMILES: Cc1cnc(NC(=O)[C@H]2CCC[C@H](C2)NC(=O)C2COC2)cc1-c1cnn2CC(C)(C)Cc12
InChI Key: InChIKey=BNMSUGRKZJRLFE-FUHWJXTLSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM454591 (US10717746, Example 76) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTRAZENECA AB US Patent | Assay Description Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o... | US Patent US10717746 (2020) BindingDB Entry DOI: 10.7270/Q2NV9N9F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM454591 (US10717746, Example 76) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <3 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTRAZENECA AB US Patent | Assay Description Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o... | US Patent US10717746 (2020) BindingDB Entry DOI: 10.7270/Q2NV9N9F | |||||||||||
More data for this Ligand-Target Pair |