null

SMILES: CC[C@H](Nc1ncnc(N)c1-c1nc(C)no1)c1nc2cccc(C#CC)c2c(=O)n1-c1ccccc1

InChI Key: InChIKey=FRYWZGFVRMFIFU-IBGZPJMESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 457853   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM457853 ((S)-2-(1-((6-amino-5-(3-methyl-1,2,4-oxadiazol-5-y...) Show SMILES CC[C@H](Nc1ncnc(N)c1-c1nc(C)no1)c1nc2cccc(C#CC)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C27H24N8O2/c1-4-10-17-11-9-14-20-21(17)27(36)35(18-12-7-6-8-13-18)25(33-20)19(5-2)32-24-22(23(28)29-15-30-24)26-31-16(3)34-37-26/h6-9,11-15,19H,5H2,1-3H3,(H3,28,29,30,32)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD.; CALITOR SCIENCES, LLC US Patent					Assay Description PI3K (p110α/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol 4,5-bisphosphate and MgATP (concentration as ...				US Patent US10751339 (2020)
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM457853 ((S)-2-(1-((6-amino-5-(3-methyl-1,2,4-oxadiazol-5-y...) Show SMILES CC[C@H](Nc1ncnc(N)c1-c1nc(C)no1)c1nc2cccc(C#CC)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C27H24N8O2/c1-4-10-17-11-9-14-20-21(17)27(36)35(18-12-7-6-8-13-18)25(33-20)19(5-2)32-24-22(23(28)29-15-30-24)26-31-16(3)34-37-26/h6-9,11-15,19H,5H2,1-3H3,(H3,28,29,30,32)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD.; CALITOR SCIENCES, LLC US Patent					Assay Description PI3K (p120γ) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol-4, 5-bisphosphate and MgATP (concentration as required)...				US Patent US10751339 (2020)
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM457853 ((S)-2-(1-((6-amino-5-(3-methyl-1,2,4-oxadiazol-5-y...) Show SMILES CC[C@H](Nc1ncnc(N)c1-c1nc(C)no1)c1nc2cccc(C#CC)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C27H24N8O2/c1-4-10-17-11-9-14-20-21(17)27(36)35(18-12-7-6-8-13-18)25(33-20)19(5-2)32-24-22(23(28)29-15-30-24)26-31-16(3)34-37-26/h6-9,11-15,19H,5H2,1-3H3,(H3,28,29,30,32)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD.; CALITOR SCIENCES, LLC US Patent					Assay Description PI3K (p110δ/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol-4, 5-bisphosphate and MgATP (concentration as...				US Patent US10751339 (2020)
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM457853 ((S)-2-(1-((6-amino-5-(3-methyl-1,2,4-oxadiazol-5-y...) Show SMILES CC[C@H](Nc1ncnc(N)c1-c1nc(C)no1)c1nc2cccc(C#CC)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C27H24N8O2/c1-4-10-17-11-9-14-20-21(17)27(36)35(18-12-7-6-8-13-18)25(33-20)19(5-2)32-24-22(23(28)29-15-30-24)26-31-16(3)34-37-26/h6-9,11-15,19H,5H2,1-3H3,(H3,28,29,30,32)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	582	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD.; CALITOR SCIENCES, LLC US Patent					Assay Description PI3K (p110β/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol-4,5-bisphosphate and MgATP (concentration as ...				US Patent US10751339 (2020)
					More data for this Ligand-Target Pair