null

SMILES: CC1(CC1)C(=O)N1CCC(O)(Cn2cnc3n(c(Cl)cc3c2=O)-c2ccc3OCOc3c2)CC1

InChI Key: InChIKey=HQHQDIGQORKBKP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 462590   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM462590 (US10766903, Example 202 | US10766903, Example 235) Show SMILES CC1(CC1)C(=O)N1CCC(O)(Cn2cnc3n(c(Cl)cc3c2=O)-c2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C24H25ClN4O5/c1-23(4-5-23)22(31)27-8-6-24(32,7-9-27)12-28-13-26-20-16(21(28)30)11-19(25)29(20)15-2-3-17-18(10-15)34-14-33-17/h2-3,10-11,13,32H,4-9,12,14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
ALMAC DISCOVERY LIMITED US Patent					Assay Description USP7 activity was monitored in a fluorescence polarisation (FP) homogeneous assay using the isopeptide ubiquitin-Lys-TAMRA substrate (U-558, Boston B...				US Patent US10766903 (2020)
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 7 (Homo sapiens (Human))	BDBM462590 (US10766903, Example 202 | US10766903, Example 235) Show SMILES CC1(CC1)C(=O)N1CCC(O)(Cn2cnc3n(c(Cl)cc3c2=O)-c2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C24H25ClN4O5/c1-23(4-5-23)22(31)27-8-6-24(32,7-9-27)12-28-13-26-20-16(21(28)30)11-19(25)29(20)15-2-3-17-18(10-15)34-14-33-17/h2-3,10-11,13,32H,4-9,12,14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	625	n/a	n/a	n/a	n/a	n/a	n/a
ALMAC DISCOVERY LIMITED US Patent					Assay Description USP7 activity was monitored in a fluorescence polarisation (FP) homogeneous assay using the isopeptide ubiquitin-Lys-TAMRA substrate (U-558, Boston B...				US Patent US10766903 (2020)
					More data for this Ligand-Target Pair