null

SMILES: Cn1cc(cn1)-c1cc2c(ncnn2c1)N1CCN(CC1)c1ncc(cn1)[C@](C)(O)c1ccc(F)cc1

InChI Key: InChIKey=NUGNCKGULUDHLA-AREMUKBSSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 469270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor alpha [D842V] (Homo sapiens (Human))	BDBM469270 (US10807985, Compound 45) Show SMILES Cn1cc(cn1)-c1cc2c(ncnn2c1)N1CCN(CC1)c1ncc(cn1)[C@](C)(O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C26H26FN9O/c1-26(37,20-3-5-22(27)6-4-20)21-13-28-25(29-14-21)35-9-7-34(8-10-35)24-23-11-18(16-36(23)32-17-30-24)19-12-31-33(2)15-19/h3-6,11-17,37H,7-10H2,1-2H3/t26-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Blueprint Medicines Corporation US Patent					Assay Description In each well of a 384-well plate, 0.7 ng/ul (8 nM) of PDGFRA D842V (ProQinase 0761-0000-1) was incubated in a total of 12.5 ul of buffer (100 mM HEPE...				US Patent US10807985 (2020)
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [D816V] (Homo sapiens (Human))	BDBM469270 (US10807985, Compound 45) Show SMILES Cn1cc(cn1)-c1cc2c(ncnn2c1)N1CCN(CC1)c1ncc(cn1)[C@](C)(O)c1ccc(F)cc1 |r| Show InChI InChI=1S/C26H26FN9O/c1-26(37,20-3-5-22(27)6-4-20)21-13-28-25(29-14-21)35-9-7-34(8-10-35)24-23-11-18(16-36(23)32-17-30-24)19-12-31-33(2)15-19/h3-6,11-17,37H,7-10H2,1-2H3/t26-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Blueprint Medicines Corporation US Patent					Assay Description In each well of a 384-well plate, 0.04 ng/ul (0.5 nM) of D816V KIT (Carna Bioscience 08-156) was incubated in a total of 12.5 ul of buffer (100 mM HE...				US Patent US10807985 (2020)
					More data for this Ligand-Target Pair