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SMILES: COc1cc(ccc1F)[C@@H](NC(=O)c1cc(CN2CCOC2=N)cc(c1)-c1cccnc1C(F)(F)F)C1CC1

InChI Key: InChIKey=RNLUQWZNZCSDDV-DEOSSOPVSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473315   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM473315
PNG
(US10844044, Example 305)
Show SMILES COc1cc(ccc1F)[C@@H](NC(=O)c1cc(CN2CCOC2=N)cc(c1)-c1cccnc1C(F)(F)F)C1CC1 |r|
Show InChI InChI=1S/C28H26F4N4O3/c1-38-23-14-18(6-7-22(23)29)24(17-4-5-17)35-26(37)20-12-16(15-36-9-10-39-27(36)33)11-19(13-20)21-3-2-8-34-25(21)28(30,31)32/h2-3,6-8,11-14,17,24,33H,4-5,9-10,15H2,1H3,(H,35,37)/t24-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...

US Patent US10844044 (2020)


BindingDB Entry DOI: 10.7270/Q21R6TKB
More data for this
Ligand-Target Pair