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SMILES: COc1cc(CNC(=O)c2cc(Cn3ccoc3=N)cc(c2)-c2cccnc2C(F)(F)F)cc(OC)c1

InChI Key: InChIKey=WJMWNKWEATWYRG-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473442   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM473442
PNG
(US10844044, Example 244)
Show SMILES COc1cc(CNC(=O)c2cc(Cn3ccoc3=N)cc(c2)-c2cccnc2C(F)(F)F)cc(OC)c1
Show InChI InChI=1S/C26H23F3N4O4/c1-35-20-10-16(11-21(13-20)36-2)14-32-24(34)19-9-17(15-33-6-7-37-25(33)30)8-18(12-19)22-4-3-5-31-23(22)26(27,28)29/h3-13,30H,14-15H2,1-2H3,(H,32,34)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...

US Patent US10844044 (2020)


BindingDB Entry DOI: 10.7270/Q21R6TKB
More data for this
Ligand-Target Pair