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SMILES: COc1cc(OC)cc(c1)C(NC(=O)c1cc(Cn2ccoc2=N)cc(c1)-c1cccnc1C(F)(F)F)C1CC1

InChI Key: InChIKey=WTIDKCAWSGFSIE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473446   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM473446
PNG
(US10844044, Example 245)
Show SMILES COc1cc(OC)cc(c1)C(NC(=O)c1cc(Cn2ccoc2=N)cc(c1)-c1cccnc1C(F)(F)F)C1CC1
Show InChI InChI=1S/C29H27F3N4O4/c1-38-22-13-20(14-23(15-22)39-2)25(18-5-6-18)35-27(37)21-11-17(16-36-8-9-40-28(36)33)10-19(12-21)24-4-3-7-34-26(24)29(30,31)32/h3-4,7-15,18,25,33H,5-6,16H2,1-2H3,(H,35,37)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
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UniChem
US Patent
<0.100n/an/an/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
A Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) assay that measures the displacement of the 10mer-Thr-FAM probe in response to compo...

US Patent US10844044 (2020)

More data for this
Ligand-Target Pair