null
SMILES: Cc1cc(Oc2ccc(cc2)S(=O)(=O)N(Cc2ccccc2)c2ccc(C(O)=O)c(O)c2)cc(C)c1Cl
InChI Key: InChIKey=MHWCKPSUVMUWFL-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human)) | BDBM473868 (4-(N-benzyl-4-(4- chloro-3,5- dimethylphenoxy) phe...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 629 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
UNIVERSITY OF MARYLAND, BALTIMORE US Patent | Assay Description Molecular modeling and SILCS functional group affinity mapping (FragMaps) of the Mcl-1 binding site indicated that the carboxylic acid of designed mo... | US Patent US10858316 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human)) | BDBM473868 (4-(N-benzyl-4-(4- chloro-3,5- dimethylphenoxy) phe...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 629 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
UNIVERSITY OF MARYLAND, BALTIMORE US Patent | Assay Description Molecular modeling and SILCS functional group affinity mapping (FragMaps) of the Mcl-1 binding site indicated that the carboxylic acid of designed mo... | US Patent US10858316 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human)) | BDBM473868 (4-(N-benzyl-4-(4- chloro-3,5- dimethylphenoxy) phe...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 659 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
UNIVERSITY OF MARYLAND, BALTIMORE US Patent | Assay Description Molecular modeling and SILCS functional group affinity mapping (FragMaps) of the Mcl-1 binding site indicated that the carboxylic acid of designed mo... | US Patent US10858316 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL) (Homo sapiens (Human)) | BDBM473868 (4-(N-benzyl-4-(4- chloro-3,5- dimethylphenoxy) phe...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
UNIVERSITY OF MARYLAND, BALTIMORE US Patent | Assay Description Molecular modeling and SILCS functional group affinity mapping (FragMaps) of the Mcl-1 binding site indicated that the carboxylic acid of designed mo... | US Patent US10858316 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL) (Homo sapiens (Human)) | BDBM473868 (4-(N-benzyl-4-(4- chloro-3,5- dimethylphenoxy) phe...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
UNIVERSITY OF MARYLAND, BALTIMORE US Patent | Assay Description Molecular modeling and SILCS functional group affinity mapping (FragMaps) of the Mcl-1 binding site indicated that the carboxylic acid of designed mo... | US Patent US10858316 (2020) | |||||||||||
More data for this Ligand-Target Pair |