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SMILES: OCc1cnc2-c3c(O)c(=O)ccn3[C@H](Cn12)C(c1ccccc1)c1ccccc1

InChI Key: InChIKey=HMADPEJNCUJIKD-LJQANCHMSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 474369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase acidic protein ()	BDBM474369 ((S)-6-benzhydryl-11-hydroxy-3- (hydroxymethyl)-5,6...) Show SMILES OCc1cnc2-c3c(O)c(=O)ccn3[C@H](Cn12)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C24H21N3O3/c28-15-18-13-25-24-22-23(30)20(29)11-12-26(22)19(14-27(18)24)21(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-13,19,21,28,30H,14-15H2/t19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)	BDBM474369 ((S)-6-benzhydryl-11-hydroxy-3- (hydroxymethyl)-5,6...) Show SMILES OCc1cnc2-c3c(O)c(=O)ccn3[C@H](Cn12)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C24H21N3O3/c28-15-18-13-25-24-22-23(30)20(29)11-12-26(22)19(14-27(18)24)21(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-13,19,21,28,30H,14-15H2/t19-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474369 ((S)-6-benzhydryl-11-hydroxy-3- (hydroxymethyl)-5,6...) Show SMILES OCc1cnc2-c3c(O)c(=O)ccn3[C@H](Cn12)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C24H21N3O3/c28-15-18-13-25-24-22-23(30)20(29)11-12-26(22)19(14-27(18)24)21(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-13,19,21,28,30H,14-15H2/t19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Neuraminidase ()	BDBM474369 ((S)-6-benzhydryl-11-hydroxy-3- (hydroxymethyl)-5,6...) Show SMILES OCc1cnc2-c3c(O)c(=O)ccn3[C@H](Cn12)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C24H21N3O3/c28-15-18-13-25-24-22-23(30)20(29)11-12-26(22)19(14-27(18)24)21(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-13,19,21,28,30H,14-15H2/t19-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
Novartis AG US Patent									US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Neuraminidase (Influenza A virus (strain A/Memphis/1/1971 H3N2))	BDBM474369 ((S)-6-benzhydryl-11-hydroxy-3- (hydroxymethyl)-5,6...) Show SMILES OCc1cnc2-c3c(O)c(=O)ccn3[C@H](Cn12)C(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C24H21N3O3/c28-15-18-13-25-24-22-23(30)20(29)11-12-26(22)19(14-27(18)24)21(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-13,19,21,28,30H,14-15H2/t19-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a
Novartis AG US Patent									US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair