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SMILES: Oc1cc(ccc1-c1cc(=O)n2nc(Cc3ccccc3)c(-c3ccc(Cl)cc3)c2[nH]1)[N+]([O-])=O

InChI Key: InChIKey=PIIUNROCGNUJNB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474987   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ADP-ribosylation factor 6


(Human)		BDBM474987
PNG
(US10849901, Compound 37)
Show SMILES Oc1cc(ccc1-c1cc(=O)n2nc(Cc3ccccc3)c(-c3ccc(Cl)cc3)c2[nH]1)[N+]([O-])=O
Show InChI InChI=1S/C25H17ClN4O4/c26-17-8-6-16(7-9-17)24-21(12-15-4-2-1-3-5-15)28-29-23(32)14-20(27-25(24)29)19-11-10-18(30(33)34)13-22(19)31/h1-11,13-14,27,31H,12H2
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 1.70n/an/an/an/an/an/a



Navigen, Inc.; The University of Utah Research Foundation

US Patent


Assay Description
The primary biochemical assay uses a fluorometric assay for monitoring the replacement of bound nucleotide with a fluorogenic GTP derivative bearing ...

US Patent US10849901 (2020)

More data for this
Ligand-Target Pair