BindingDB logo
myBDB logout

null

SMILES: COc1ccc(CS(=O)(=O)c2cc3nc([nH]c3cc2Cl)-n2cc(cn2)C(O)=O)cc1

InChI Key: InChIKey=OHRLKYYIBYULOB-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 475479   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Egl nine homolog 1 [181-417]


(Homo sapiens (Human))		BDBM475479
PNG
(1-[6-Chloro-5-(4-methoxy-phenylmethanesulfonyl)-1H...)
Show SMILES COc1ccc(CS(=O)(=O)c2cc3nc([nH]c3cc2Cl)-n2cc(cn2)C(O)=O)cc1
Show InChI InChI=1S/C19H15ClN4O5S/c1-29-13-4-2-11(3-5-13)10-30(27,28)17-7-16-15(6-14(17)20)22-19(23-16)24-9-12(8-21-24)18(25)26/h2-9H,10H2,1H3,(H,22,23)(H,25,26)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 20n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...

US Patent US10851083 (2020)

More data for this
Ligand-Target Pair