null

SMILES: COc1ccc(cc1)S(=O)(=O)c1cc2nc([nH]c2cc1C(F)(F)F)-n1cc(cn1)C(O)=O

InChI Key: InChIKey=IUZFUIBUQSSUDM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475550   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475550 (1-[5-(4-Methoxy-benzenesulfonyl)-6-trifluoromethyl...) Show SMILES COc1ccc(cc1)S(=O)(=O)c1cc2nc([nH]c2cc1C(F)(F)F)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C19H13F3N4O5S/c1-31-11-2-4-12(5-3-11)32(29,30)16-7-15-14(6-13(16)19(20,21)22)24-18(25-15)26-9-10(8-23-26)17(27)28/h2-9H,1H3,(H,24,25)(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475550 (1-[5-(4-Methoxy-benzenesulfonyl)-6-trifluoromethyl...) Show SMILES COc1ccc(cc1)S(=O)(=O)c1cc2nc([nH]c2cc1C(F)(F)F)-n1cc(cn1)C(O)=O Show InChI InChI=1S/C19H13F3N4O5S/c1-31-11-2-4-12(5-3-11)32(29,30)16-7-15-14(6-13(16)19(20,21)22)24-18(25-15)26-9-10(8-23-26)17(27)28/h2-9H,1H3,(H,24,25)(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair