null

SMILES: OC(=O)c1cnn(c1)-c1nc2cc(SCc3ccc(cc3)-c3ccccc3C#N)c(Cl)cc2[nH]1

InChI Key: InChIKey=DDJVVJGNEZNBNR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475560   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475560 (1-[6-Chloro-5-(2'-cyano-biphenyl-4-ylmethylsulfany...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(SCc3ccc(cc3)-c3ccccc3C#N)c(Cl)cc2[nH]1 Show InChI InChI=1S/C25H16ClN5O2S/c26-20-9-21-22(30-25(29-21)31-13-18(12-28-31)24(32)33)10-23(20)34-14-15-5-7-16(8-6-15)19-4-2-1-3-17(19)11-27/h1-10,12-13H,14H2,(H,29,30)(H,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475560 (1-[6-Chloro-5-(2'-cyano-biphenyl-4-ylmethylsulfany...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(SCc3ccc(cc3)-c3ccccc3C#N)c(Cl)cc2[nH]1 Show InChI InChI=1S/C25H16ClN5O2S/c26-20-9-21-22(30-25(29-21)31-13-18(12-28-31)24(32)33)10-23(20)34-14-15-5-7-16(8-6-15)19-4-2-1-3-17(19)11-27/h1-10,12-13H,14H2,(H,29,30)(H,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair