null

SMILES: OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1ccc(Cl)cc1

InChI Key: InChIKey=YDKTXLMBLOTICX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475561   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475561 (1-[6-Chloro-5-(4-chloro-phenylmethanesulfonyl)-1H-...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C18H12Cl2N4O4S/c19-12-3-1-10(2-4-12)9-29(27,28)16-6-15-14(5-13(16)20)22-18(23-15)24-8-11(7-21-24)17(25)26/h1-8H,9H2,(H,22,23)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...				Citation and Details BindingDB Entry DOI: 10.7270/Q2V69PHV
					More data for this Ligand-Target Pair
Egl nine homolog 1 [181-417] (Homo sapiens (Human))	BDBM475561 (1-[6-Chloro-5-(4-chloro-phenylmethanesulfonyl)-1H-...) Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C18H12Cl2N4O4S/c19-12-3-1-10(2-4-12)9-29(27,28)16-6-15-14(5-13(16)20)22-18(23-15)24-8-11(7-21-24)17(25)26/h1-8H,9H2,(H,22,23)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...				US Patent US10851083 (2020) BindingDB Entry DOI: 10.7270/Q25B05K9
					More data for this Ligand-Target Pair