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SMILES: OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1ccc(cc1)-c1ccccc1C#N

InChI Key: InChIKey=VAGRXEYATXSNCW-UHFFFAOYSA-N

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 475569   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Egl nine homolog 1 [181-417]


(Homo sapiens (Human))		BDBM475569
PNG
(1-[6-Chloro-5-(2'-cyano-biphenyl-4-ylmethanesulfon...)
Show SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1ccc(cc1)-c1ccccc1C#N
Show InChI InChI=1S/C25H16ClN5O4S/c26-20-9-21-22(30-25(29-21)31-13-18(12-28-31)24(32)33)10-23(20)36(34,35)14-15-5-7-16(8-6-15)19-4-2-1-3-17(19)11-27/h1-10,12-13H,14H2,(H,29,30)(H,32,33)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 20n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...

US Patent US10851083 (2020)

More data for this
Ligand-Target Pair