null
SMILES: Nc1ncnc2n(nc(Sc3ccccc3)c12)[C@@H]1O[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]1O
InChI Key: InChIKey=YHRJIUXBQBEGPM-UBEDBUPSSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ubiquitin-like modifier-activating enzyme ATG7 (Homo sapiens (Human)) | BDBM476025 (US10865208, Compound I-82 | {(2R,3S,4R,5R)-5-[4-am...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
MILLENNIUM PHARMACEUTICALS, INC. US Patent | Assay Description The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ... | US Patent US10865208 (2020) BindingDB Entry DOI: 10.7270/Q23B6366 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubiquitin-like modifier-activating enzyme ATG7 (Homo sapiens (Human)) | BDBM476025 (US10865208, Compound I-82 | {(2R,3S,4R,5R)-5-[4-am...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 201 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.bmc.2020.115681 BindingDB Entry DOI: 10.7270/Q2M90DBR | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubiquitin-like modifier-activating enzyme ATG7 (Homo sapiens (Human)) | BDBM476025 (US10865208, Compound I-82 | {(2R,3S,4R,5R)-5-[4-am...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.bmc.2020.115681 BindingDB Entry DOI: 10.7270/Q2M90DBR | ||||||||||||
More data for this Ligand-Target Pair |