null

SMILES: C[C@H]1CN(Cc2cc(Nc3ncc(Cl)c(n3)-c3c[nH]c4cc(F)ccc34)cc(c2)C2CC2)C[C@@H](C)N1CCO

InChI Key: InChIKey=GNZBRCVHYABOOV-KDURUIRLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 476696   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM476696 (2-((2R,6S)-4-(3-((5-chloro-4-(6-fluoro-1H-indole-3...) Show SMILES C[C@H]1CN(Cc2cc(Nc3ncc(Cl)c(n3)-c3c[nH]c4cc(F)ccc34)cc(c2)C2CC2)C[C@@H](C)N1CCO Show InChI InChI=1S/C30H34ClFN6O/c1-18-15-37(16-19(2)38(18)7-8-39)17-20-9-22(21-3-4-21)11-24(10-20)35-30-34-14-27(31)29(36-30)26-13-33-28-12-23(32)5-6-25(26)28/h5-6,9-14,18-19,21,33,39H,3-4,7-8,15-17H2,1-2H3,(H,34,35,36)/t18-,19+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dimer of Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM476696 (2-((2R,6S)-4-(3-((5-chloro-4-(6-fluoro-1H-indole-3...) Show SMILES C[C@H]1CN(Cc2cc(Nc3ncc(Cl)c(n3)-c3c[nH]c4cc(F)ccc34)cc(c2)C2CC2)C[C@@H](C)N1CCO Show InChI InChI=1S/C30H34ClFN6O/c1-18-15-37(16-19(2)38(18)7-8-39)17-20-9-22(21-3-4-21)11-24(10-20)35-30-34-14-27(31)29(36-30)26-13-33-28-12-23(32)5-6-25(26)28/h5-6,9-14,18-19,21,33,39H,3-4,7-8,15-17H2,1-2H3,(H,34,35,36)/t18-,19+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
HANMI PHARM. CO.. LTD. US Patent					Assay Description The inhibitory activity of some of the compounds described above against FLT3-ITD, FLT3 wild type (WT), VEGFR2 (KDR), and SYK kinase was measured.The...				US Patent US10870639 (2020)
					More data for this Ligand-Target Pair