null

SMILES: Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN2CC(C2)C(O)=O)cc1Cl

InChI Key: InChIKey=AMMMZTWNZMLTJF-KDXMTYKHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 482362   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM482362 (US10919852, Compound TABLE 1.61 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN2CC(C2)C(O)=O)cc1Cl |r| Show InChI InChI=1S/C42H45ClN4O6/c1-27-33(5-3-8-38(27)51-16-4-13-46-14-11-32(48)12-15-46)34-6-2-7-36-35(34)9-10-39(36)53-41-19-40(52-26-29-17-28(20-44)21-45-22-29)30(18-37(41)43)23-47-24-31(25-47)42(49)50/h2-3,5-8,17-19,21-22,31-32,39,48H,4,9-16,23-26H2,1H3,(H,49,50)/t39-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q22N56DJ
					More data for this Ligand-Target Pair
Programmed cell death protein 1 (Homo sapiens)	BDBM482362 (US10919852, Compound TABLE 1.61 | US11708326, Comp...) Show SMILES Cc1c(OCCCN2CCC(O)CC2)cccc1-c1cccc2[C@H](CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CN2CC(C2)C(O)=O)cc1Cl |r| Show InChI InChI=1S/C42H45ClN4O6/c1-27-33(5-3-8-38(27)51-16-4-13-46-14-11-32(48)12-15-46)34-6-2-7-36-35(34)9-10-39(36)53-41-19-40(52-26-29-17-28(20-44)21-45-22-29)30(18-37(41)43)23-47-24-31(25-47)42(49)50/h2-3,5-8,17-19,21-22,31-32,39,48H,4,9-16,23-26H2,1H3,(H,49,50)/t39-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. US Patent					Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...				US Patent US10919852 (2021) BindingDB Entry DOI: 10.7270/Q2RF5Z3R
					More data for this Ligand-Target Pair