BDBM482571 US10919852, Compound TABLE 1.270
SMILES: Clc1cc(CNC[C@@H]2CCC(=O)N2)c(OCc2cncc(c2)C#N)cc1O[C@H]1CCc2c1cccc2-c1cccc(OCCCN2CCC2)c1Cl
InChI Key: InChIKey=AYMRRFYKXREYBB-YTWZBVJHSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Programmed cell death protein 1 (Homo sapiens) | BDBM482571![]() (US10919852, Compound TABLE 1.270) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <5 | n/a | n/a | n/a | n/a | n/a | n/a |
ChemoCentryx, Inc. US Patent | Assay Description 96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W... | US Patent US10919852 (2021) | |||||||||||
More data for this Ligand-Target Pair |