null
SMILES: CCCCNCc1ccc(Cn2c(O)nc3c(N)nc(OCCCC)nc23)cn1
InChI Key: InChIKey=CTXXUOZHIDMMJN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Interleukin-6 (Homo sapiens (Human)) | BDBM483337![]() (US10919895, Compound Ic-01) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 26 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Compounds diluted in DMSO were transferred to individual wells of a Matrix Technologies clear, V-bottom 384-well plate using ECHO acoustic liquid han... | US Patent US10919895 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Toll-like receptor 7 (Homo sapiens (Human)) | BDBM483337![]() (US10919895, Compound Ic-01) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description Engineered human embryonic kidney blue cells (HEK-Blue™ TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) ... | US Patent US10919895 (2021) | |||||||||||
More data for this Ligand-Target Pair |