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SMILES: Fc1ccc(cc1)-n1cc(-c2cccc(c2)-c2ccccc2)c2ccc(cc12)C(=O)NC1CCS(=O)(=O)C1

InChI Key: InChIKey=NOZXNLFGQCGULP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 486405   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Diacylglycerol O-acyltransferase 2


(Homo sapiens (Human))		BDBM486405
PNG
(3-biphenyl-3-yl-N-(1,1- dioxidotetrahydrothiophen-...)
Show SMILES Fc1ccc(cc1)-n1cc(-c2cccc(c2)-c2ccccc2)c2ccc(cc12)C(=O)NC1CCS(=O)(=O)C1
Show InChI InChI=1S/C31H25FN2O3S/c32-25-10-12-27(13-11-25)34-19-29(23-8-4-7-22(17-23)21-5-2-1-3-6-21)28-14-9-24(18-30(28)34)31(35)33-26-15-16-38(36,37)20-26/h1-14,17-19,26H,15-16,20H2,(H,33,35)
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PC cid
PC sid
UniChem
US Patent
n/an/a 61n/an/an/an/an/an/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...

US Patent US10947222 (2021)

More data for this
Ligand-Target Pair