null
SMILES: Fc1ccc(cc1)-n1cc(-c2c(F)cccc2Cl)c2ccc(cc12)C(=O)NC1CCS(=O)(=O)C1
InChI Key: InChIKey=DUKHKRDYKLQNCF-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human)) | BDBM486419![]() (3-(2-chloro-6-fluorophenyl)-N- (1,1-dioxidotetrahy...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 155 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m... | US Patent US10947222 (2021) | |||||||||||
More data for this Ligand-Target Pair |