BDBM487971 4-(4-((5-chloro-2-methyl-6-(2H- 1,2,3-triazol-2-yl)pyridin-3- yl)carbamoyl)-5- (trifluoromethyl)-1H-pyrazol-1- yl)thieno[2,3-c]pyridine-7- carboxamide::US10954214, Compound 393

SMILES: Cc1nc(c(Cl)cc1NC(=O)c1cnn(c1C(F)(F)F)-c1cnc(C(N)=O)c2sccc12)-n1nccn1

InChI Key: InChIKey=SFWKTIMVKFWOKX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487971   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM487971 (4-(4-((5-chloro-2-methyl-6-(2H- 1,2,3-triazol-2-yl...) Show SMILES Cc1nc(c(Cl)cc1NC(=O)c1cnn(c1C(F)(F)F)-c1cnc(C(N)=O)c2sccc12)-n1nccn1 Show InChI InChI=1S/C21H13ClF3N9O2S/c1-9-13(6-12(22)19(31-9)34-28-3-4-29-34)32-20(36)11-7-30-33(17(11)21(23,24)25)14-8-27-15(18(26)35)16-10(14)2-5-37-16/h2-8H,1H3,(H2,26,35)(H,32,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...				US Patent US10954214 (2021)
					More data for this Ligand-Target Pair