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SMILES: FC(F)(F)c1c(cnn1-c1cnc(C2CC2)c2sccc12)C(=O)Nc1cnc(c(Cl)c1)-n1nccn1

InChI Key: InChIKey=RZQJIPFUUFOCQM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488013   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1


(Homo sapiens (Human))		BDBM488013
PNG
(N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...)
Show SMILES FC(F)(F)c1c(cnn1-c1cnc(C2CC2)c2sccc12)C(=O)Nc1cnc(c(Cl)c1)-n1nccn1
Show InChI InChI=1S/C22H14ClF3N8OS/c23-15-7-12(8-28-20(15)34-29-4-5-30-34)32-21(35)14-9-31-33(19(14)22(24,25)26)16-10-27-17(11-1-2-11)18-13(16)3-6-36-18/h3-11H,1-2H2,(H,32,35)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 170n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...

US Patent US10954214 (2021)


BindingDB Entry DOI: 10.7270/Q2SX6HB1
More data for this
Ligand-Target Pair